Endocrine Abstracts

A 76-year-old female patient has been admitted to various hospitals with complaints of low blood sugar especially in the morning, sweating, fainting, loss of consciousness, have been suspected of insulinoma with the results of the latest examinations made in 2012, but no focus has been detected. With the same complaints, the patient who applied to our out-patient clinic in December 2017 was subjected to an extended hunger test and invested for further research. Previously, the...

Case: A 51-year-old-woman was referred to endocrinology outpatient clinic due to a thyroid nodule 9 mm in diameter. Fine needle aspiration (FNA) biopsy revealed papillary thyroid carcinoma and she was directed to surgery. The surgeon decided to perform subtotal thyroidectomy due to the small nodule size. Pathologic examination showed the histology to be consistent with tall cell carcinoma. Complementary total thyroidectomy was proposed to the patient but she did not accept the...

The frequency of adrenal masses is increasing in parallel with the progress of the technology. Most of these masses, which are detected by chance, are not functional, and only a part of them are exposed to an excess of hormone. The most common dysfunction in masses with hormonal activity is hypercortisolism. However, the diagnosis of Cushing’s disease is based on more than one test. In this study, we intended to compare the values of screening tests to determine whether t...

Background and aims: Neuropeptide Y (NPY) cause decrease glomerular filtration rate, aldosterone concentration, and plasma renin activity by stimulating NPY receptors in the kidney. Previous studies have suggested that NPY polymorphism is related to development of advanced diabetic nephropathy (DN). The aim of this study was to evaluate the relationship between the serum neuropeptide Y levels and different stages of DN in patients with type 2 diabetes mellitus (T2DM).<p cl...

Background and aims: Orexins are hypothalamic neuropeptides involved in energy homeostasis and sleep regulation. We aimed to find the relation between serum orexin-A levels, glucose, and insulin levels, depression and sleep problems in patients with metabolic syndrome.Materials and methods: This descriptive, cross-sectional study included 43 patients with metabolic syndrome (patient) and 16 healthy subjects (control, age, and sex matched) who applied to ...

Introduction: Polycystic ovary syndrome (PCOS) is widely diagnosed among young women in reproductive age. Vitamin D deficiency has been known as a common problem in all ages and also in a recent study which performed in a small study groups, reported that it may accompany with hyperandrogenism. The aim of our study is to evaluate serum 25(OH)D3 levels in PCOS patients compared with healthy control and relation to androgen levels.Methods: Forty...

Aim: Paraoxonase-1 (PON-1), an HDL-associated enzyme has been shown to possess antioxidant properties that protect against atherosclerosis. The aim of this study is to evaluate serum paraoxanase activities, lipid profiles and carotid intimae media thickness (CIMT) as an early marker of atherosclerosis in healthy man and women.Method: Four hundred healthy volunteers (F/M: 250/150, 19–23 years) included in the study. Serum paraoxonase and arylesterase...

Recent studies indicate that atherosclerotic process is associated with bone metabolism. The aim of this study was to evaluate carotid intima media thickness (CIMT) and its association with bone mineral density and bone turnover markers as well as inflammation markers in type 2 diabetic male patients.Material-method: 184 type 2 diabetic males (56±8 y) and 85 non-diabetic control subjects (52±7 y) were recruited. Bone mineral density was measure...

Symptomatic hyperparathyroid patients are under risk of increased cardiovascular mortality, associated with left ventricular hypertrophy, diastolic dysfunction and accelerated atherosclerosis. Data on asymptomatic hyperparathyroid patients are conflicting. This study aimed to determine diastolic dysfunction and its association with carotis intima media thickness (CIMT) and flow-mediated vasodilation (FMD) in a group of asymptomatic hyperparathyroid patients.<p class="abste...

Objective: Low skeletal muscle mass is an emerging risk factor for metabolic disorders. In this study, we aimed to evaluate the relationships between fat mass, muscle mass, muscle fat mass ratio, total fat mass, and abdominal fat mass ratio by comparing the body compositions in obese women with and without metabolic syndrome.Methods: Totally 89 obese women (mean±S.D., age 42.1±12 years, BMI 36.5±4.2%) with newly diagnosed me...